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pentobarbital will reduce the extent or impact of lopinavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.pentobarbital will lower the level or effect of theophylline by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.Formulated during the 1930s, Nembutal immediately grew to become a well kno